Manchester United will begin the defense of their English Premier League title with a trip to Swansea City, while Jose Mourinho will taste Premier League action for the first time in six years when his side host newly-promoted Hull City.
Arsenal and Arsene Wenger, with what many hope will be a significantly strengthened squad, will entertain Aston Villa when the Premier League kicks off on August 17, while Manuel Pellegrini's reign as Manchester City manager starts with a game against Newcastle United at the Etihad in another intriguing fixture.
David Moyes will have a tricky first game on his hands as Manchester United manager, with Swansea, under Michael Laudrup, a team capable of beating any side on their day.
The big-game season starts in the second week, with United set to await the visit of Mourinho and Chelsea, while the spicy North London Derby is slated a week later on the weekend of August 31-September 1 at the Emirates, with the reverse fixture on March 15.
The same weekend, United face another tough battle in the big Derby game against Liverpool, making the first three games of Moyes' reign a far from straightforward one.
The Manchester Derbies are slated for mid-September and early March, with the season set to end on May 11.
Three potential title contenders - Manchester United, Chelsea and Arsenal -- all play away on the final week of the season, while City are at home against West Ham.
Opening day fixtures: Arsenal vs Aston Villa; Chelsea vs Hull City; Crystal Palace vs Tottenham Hotspur; Liverpool vs Stoke City; Manchester City vs Newcastle United; Norwich City vs Everton; Sunderland vs Fulham; Swansea City vs Manchester United; West Bromwich Albion vs Southampton; West Ham United vs Cardiff City.
To see the entire Premier League fixture list for the 2013-14 season, click here.