The St. Louis Rams will host their NFC West division rivals, the San Francisco 49ers, in a Week 4 Thursday Night Football matchup as they look to regain control over their season.

The Rams could be the team to give the 49ers their third consecutive loss of the season, but are coming off a tough loss themselves on the road at the hands of the Dallas Cowboys.

Quarterback Sam Bradford has improved in 2013 passing for 91 yards and six touchdowns, but, was sacked six times after not being taken down once in four straight games dating to last season.

Defensively they've been one of the worst teams in the league on paper after allowing 28.7 points and 393 total yards per game.

"All you have to do is put on a series here or a series there of our matchup last year, either one of the two games against the 49ers, and we'll have their attention," said St. Louis head coach Jeff Fisher.

As for the 49ers, since their 34-28 season opening win against the Green Bay Packers, they've looked nothing like the team they were expected to be as they chase for their second straight NFC title. In the last two games they've managed just 461 total yards, turned the ball over seven times and committed 18 penalties while being outscored 56-10 by the Seattle Seahawks and Indianapolis Colts.

Prediction:

The 49ers will bounce back and regain control over their season; 49ers 31- Rams 17

Game Time: 8:25 p.m. ET.

Location: Edward Jones Dome, St. Louis, MO

TV: NFL Network