The Detroit Lions likely will be without Calvin Johnson and Reggie Bush for Week 6 against the Vikings and fantasy football owners now will have to replace him and Golden Tate could be the best option along with Jeremy Ross, while owners of Eric Ebron and Joique Bell should expect increased targets from Matthew Stafford, who should still be a strong starter option even with Johnson out.

Johnson is dealing with an ankle injury and there is a chance that he could miss multiple games and that the injury could linger through the season. According to ESPN.com, Johnson will be out for this week and that he also could be in danger of missing multiple games. Fantasy owners should look at Golden Tate as the best replacement option, while Ross could be a solid pickup in deeper leagues. Pro Football Talk reports that Reggie Bush will be ready to go despite missing practice, while Joique Bell is dealing with a concussion.