Menelik Watson (Oakland Raiders): Derek Carr loses a key role player as Watson has ruptured his Achilles and is finished for the season. He was drafted by the Raiders in 2013 and played the majority of games in 2014.

Donovan Smith (Tampa Bay Buccaneers): Suffered a lower body injury in the Bucs third preseason game. He was seen with a walking boot during practice on Monday which usually means it is some kind of high ankle sprain. This injury will likely keep Smith out for a little while but it does not seem like his week 1 regular season status is in question.

Charles Tillman (Carolina Panthers): The Carolina Panthers new cornerback suffered a concussion in the first quarter of the Panthers third preseason game. Tillman took a huge shot to the helmet when attempting to return an interception.

Andre Branch (Jacksonville Jaguars): Defensive end Andre Branch suffered a sprained MCL in his left knee during the Jaguars preseason game on Friday. He is slated to miss the first regular season game.

TY Hilton (Indianapolis Colts): Hilton suffered a concussion during Saturday's preseason game and is currently going through the NFL's concussion protocol. Hilton will need to be cleared in order to play in the regular season opener.