Mychal Kendricks (Philadelphia Eagles) (LB): Kendricks aggravated his hamstring injury and was on the sidelines for the rest of the game.
Byron Maxwell (Philadelphia Eagles) (DB): Maxwell suffered a quad injury in the Eagles week 4 matchup.
Lane Johnson (Philadelphia Eagles) (T): Johnson has apparently sprained his MCL and his ankle so he is at best questionable for his week 5 matchup.
MarQueis Gray (Buffalo Bills) (TE): Gray suffered a broken forearm which will likely end his season for the Bills.
Aaron Colvin (Jacksonville Jaguars) (DB): Colvin suffered a shoulder injury in the Jaguars week 4 matchup with the Colts.
Devon Kennard (New York Giants) (LB): Kennard suffered a hamstring injury late in the Giants matchup with the Bills.
T.J. Carrie (Oakland Raiders) (DB): Carrie suffered a chest injury during Oakland's matchup with the Bears, it is not known how much time he will miss.
Jordan Reed (Washington Redskins) (TE): Reed suffered a concussion in Washington's week 5 contest, which paints a potentially grim picture for their tight end position if Reed cannot get cleared.
Malcom Floyd (San Diego Chargers) (WR): Malcom Floyd was knocked out of Sunday's contest with a concussion.
Stevie Johnson (San Diego Chargers) (WR): Johnson suffered a hamstring injury midway through Sunday's game and should be questionable for week 5.
Paul Posluszny (Jacksonville Jaguars) (LB): The Jacksonville linebacker is dealing with a high ankle sprain and should miss a few weeks.
Daniel Fells New York Giants (TE): Fells has a Staph infection in his ankle and will require surgery, his season is most likely finished.
Antrel Rolle (Chicago Bears)(FS): Rolle is dealing with a high ankle sprain and should miss a couple of weeks.
Cecil Shorts (Houston Texans) (WR): Cecil Shorts was having an excellent game until he dislocated his shoulder. His timetable is currently unknown.
Alec Ogletree (St. Louis Rams) (LB): Ogletree will need surgery on his injured ankle making him a candidate for IR recall/return however this is a big blow to the run stopping power of the St. Louis defense.
Lance Dunbar (Dallas Cowboys) (RB): Dunbar has probably the most gruesome injury we have seen in week 4. Dunbar's leg appeared to twist awkwardly during a return forcing him to fling the ball into the air in pain which almost cost the Cowboys a touchdown. Dunbar was carted off with tears in his eyes, it was clear to the people who have seen the injury live that it is likely he has suffered a torn ACL/MCL and will be out for the remainder of the season.
Sean Lee (Dallas Cowboys) (LB): Lee suffered a concussion late in the Sunday night contest against the Saints.
Kareem Jackson (Houston Texans) (DB): Suffered a concussion in Sunday's matchup.
Cody Latimer (Denver Broncos) (WR): Latimer was a preseason favorite to win the Broncos number 3 or 2 wide receiving job. Now Latimer is not remotely on fantasy radars and he is dealing with a groin injury.
Joe Haden (Cleveland Browns) (DB): Haden in addition to recovering from bruised ribs, it has been announced that Haden is also dealing with a broken finger.