The Philadelphia Eagles are heading into their matchup against the New York Giants pretty banged up. Despite the long week, the Eagles are dealing with plenty of injuries on offense that will make their depth pretty thin as they enter an NFC East rivalry game. Both Ryan Mathews and Nelson Agholor are dealing with injuries that will put pressure on the rest of the offense to improve.

If DeMarco Murray wants more carries, this is his game to get them. The running back will be the workhorse against the Giants with Mathews injured. According to ESPN's Phil Sheridan of ESPN, Mathews is dealing with hamstring injuries that have left him limited in practice. The Eagles are not saying what his availability will be in Week 6, but expect Murray to get the brunt of the carries in the game. He is coming off a game where he had a season-high 83 yards off 20 carries and that could improve.

"I think guys were making plays," Murray said, via ESPN.com. "Obviously, the offensive line blocked very well. We were able to convert on more third downs and get more plays and kind of get a rhythm going. We can continue to do that. I'm more comfortable. But I think every day, it's something you have to work on to stay sharp."

With Darren Sproles having gone silent on the field in the last two games, Sam Bradford will be pushing Murray on the field. The quarterback is looking to build off the momentum against New Orleans as he faces an NFC East opponent. The passing game will be critical as the Eagles could be missing Nelson Agholor in the game.

Sheridan reports that Agholor will be out for Week 6 with an ankle injury. That means Josh Huff will be the favored player in the game with Jordan Matthews and Riley Cooper. The wide receivers have seen their struggles this year. Both Matthews and Cooper have struggled with drops. Huff is hopeful that he and the receivers can target weaknesses in the Giants.

"I have respect for all the opponents we go up against," Huff said, via ESPN.com. "But everybody has their weakness. I mean, I have weaknesses. I'm pretty sure they can see that. I'm working on my weaknesses and I'm pretty sure they're working on their weaknesses."

According to ESPN Fantasy Football Insiders, Zach Ertz could be the player to bank on in this matchup. All season the Giants have struggled to defend the tight end across the middle of the field. Ertz has been putting on a great start to the season and could really capitalize off defensive weaknesses in this game.