Todd Gurley VS Cleveland Browns: Gurley will look to post another 100 yard game and get his first touchdown of the year against a Browns team that has given up the 3rd most points in fantasy to running backs this season. Gurley had 146 yards on the Cardinals and 159 on the Packers just imagine what he is going to do to the Browns.
Latavius Murray at San Diego Chargers: Murray is coming off of a bye week so he should be well rested and healthier than he was when he played Denver. Murray has had 100 yards only one time this season however he will get another opportunity as the San Diego Chargers have given up the 2nd most fantasy points to running backs all season long.
Frank Gore VS New Orleans Saints: The Saints have given up the 5th most points to fantasy running backs this season and that could mean a big week for Frank Gore. Gore should have no problem exploiting the 30th ranked run defense in the NFL.
Lamar Miller VS Houston Texans: Miller was being absolutely under-utilized under Joe Philbin, now new head coach Dan Campbell has him as his lead back and owners saw the benefit of that last week. Miller is facing a defense that gives up the 14th most fantasy points to running backs but that may not matter as Miller has suddenly caught fire. Miller ran for 100 yards against the Titans so expect more of the same game plan from head coach Dan Campbell.