Celtic suffered a heartbreaking defeat to Barcelona in their previous Champions League game at the Nou Camp, with Jordi Alba scoring the winner in the final minute of stoppage time. When the Champions League favorites arrive in Glasgow to take on the Scottish champions, Celtic will need a minor miracle to stop the Barcelona juggernaut.
Barcelona lead Group G with nine points from three games, and know a win will guarantee them a spot in the next round, while Celtic, who are second with four points, will look to at least salvage a point against the Spanish powerhouses.
"It will be a very special evening," Celtic manager Neil Lennon said. "It'll be a Champions League game, we'll play probably the best team in the world and it's the anniversary of the club. I have watched Barcelona on many occasions.
"In recent away games, Barcelona dominate possession to the point where it's 70-30. We have no reason to expect to have possession -- we accept we'll concede ground and the ball at times because they are the best in the world at keeping possession.
"If we get something out of the game, it'll give us a strong foothold in the group. We want to get a positive result. We know it's going to be hugely difficult -- I can't see any weaknesses in Barcelona.
"They are strong in every part of the park. We hope we can catch Barcelona on an off night. We need to keep the ball better but it's easier said than done. They don't change -- they force other teams to change."
Celtic might have to do without their prime striker Gary Hooper, who has a hamstring problem, while Lennon hopes Giorgios Samaras, who scored against Barcelona, will make a return from injury.
Barcelona have defensive problems with Adriano joining the injury list that includes the likes of Carles Puyol, although Gerard Pique might be available.
"Pique is an option and he has a chance of playing. He's been training well but it's a risk to play him. He hasn't played in a long while and tall players take longer to recover. Although he's been training well in recent weeks, it's hard to say when he'll be 100 percent. It's important to get players back, even more so central defenders, so it'll be good when we have Pique and Puyol again."
Barcelona manager Tito Vilanova is determined to take all three points and ensure progress into the next round. "This is our most important game in the group stage because we need to win it to qualify, regardless of the result in the other match," he said. "We'll be able to rest players once we have qualified.
"I've never been here before but I've heard about the stadium and about the atmosphere. It's difficult to beat Celtic -- we had problems at home and we only won it in the final minute. They're very good at set pieces and on the counterattack."
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Expected lineups: Celtic: Forster; Matthews, Ambrose 20, Wilson, Miku 49; Brown, Wanyama, Ledley, Mulgrew; Samaras, Watt.
Barcelona: Valdes; Alves 39, Mascherano, Busquets, Alba; Xavi, Iniesta, Pedro, Fabregas; Messi, Villa.
Prediction: 3-1 to Barcelona
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