Doug Martin at Atlanta Falcons: The Falcons have given up the 3rd most fantasy points to running back in the NFL. Martin has been on an absolute roll since week 4 and should see around 20 carries in this game. Martin has had back to back 100 yard games with 3 touchdowns in that span. Look for Martin to find some holes in this defense as he looks for his fourth 100 yard game.
Marshawn Lynch at Dallas Cowboys: Lynch has shown he is fully healthy after rushing for over 100 yards and a touchdown last week against the 49ers. Now he will get a Cowboys defense that has given up the 4th most fantasy points to running backs this season. The Cowboys defensive line does have their original starters back in the lineup so things could get interesting in Dallas.
Todd Gurley VS San Francisco 49ers: Gurley is set to break history with even an average game and should not be deterred by a defense that has given up 113.3 yards to running backs a game and has allowed 7 rushing touchdowns. Gurley has been on fire all season long and this matchup should continue his hot streak. Gurley should find the end zone twice in what should be a tremendously physical matchup.
Chris Johnson at Cleveland Browns: The Browns have given up the most points to running backs in the entire league so this matchup is fantastic. This game should be a blow out so Johnson could see a lot of time on the field as well. He should have no problem breaking 100 yards against this porous defense.