Oakland Raiders
Amari Cooper/Michael Crabtree (Wide Receivers): The Lions have given up the 7th most fantasy points to wide receivers and last week's win against the Packers was more about the Lion's pride and the Packers offensive ineffectiveness than it was about the Lion's secondary. Cooper and Crabtree should be able to carve up this Lion's secondary pretty easily. With Cooper seeing 9 plus targets a game this could be big game for the rookie.
Latavius Murray (Running Back): The Vikings kept Murray under control last week but their defense is as good as advertised. Murray should be back to strong RB2 form next week against the Lions as they give up the 12th most fantasy points to running backs in 2015. Murray should see a lot of carries in this game.
Detroit Lions
Calvin Johnson (Wide Receiver): Oakland has a pretty decent secondary and they are in the middle of the pack when it comes to how many points they give up to wide receivers. Johnson will need to be in top form if he wants to make more of an impact. In a game against the team that has given up the most fantasy points to wide receivers this year he only had 5 receptions and 85 yards. Johnson will still be a highly valued fantasy option but temper your expectations.
Eric Ebron (Tight End): Oakland has given up the 3rd most fantasy points to tight ends so it is very possible Stafford finds Ebron open a lot in this game. It is expected that Johnson will draw the double team so it will be likely Stafford uses Ebron as his primary receiving threat for when Johnson is covered.