Buffalo Bills
Sammy Watkins (Wide Receiver): New England has given up a lot of points to wide receivers but they do have a solid secondary when they need it to be. Watkins floor is easily 0 points so a good matchup hopefully means good production. With Watkins anything is possible as long as he is healthy.
LeSean McCoy/Karlos Williams (Running Backs): McCoy will look to continue his 100 yard game streak against the undefeated Patriots. The Patriots have given up the fewest points to fantasy running backs all season long so expect McCoy to see a stout defensive line. The last time these two teams met McCoy had 89 yards and no touchdown. Williams seems to be the red zone running back which should help to give him a productive week 11. Last week he struggled against the Jets but already has a touchdown versus the Patriots earlier this year. Williams is a solid flex play for week 11.
New England Patriots
Tom Brady (Quarterback): Brady murders the Bills and has had at least two touchdown passes in every game this season. There is no reason you wouldn't start.....period.
Rob Gronkowski (Tight End): Gronk had 113 yards and a touchdown against the Bills the last time these two teams met. He is currently coming off of a 100 plus yard game and is sitting at 8 touchdowns on the season. Gronk is the elite tight end so he should be matchup proof especially with Julian Edelman out.
Danny Amendola/ Brandon LaFell (Wide Receivers): Amendola and LaFell will help fill the void Edelman has left. Amendola saw the majority of his targets last week, so look for him to be the immediate replacement. Buffalo is not that great at stopping opposing wide receivers so Amendola could have a huge game.
LeGarrette Blount (Running Backs): Blount is now the dominant back in this offensive rotation, in fact in his first week as the lead rusher he had the second most carries he has had all season long. The Bills are a tough matchup to handle as Blount looks to keep his starting role however he is the primary goal line back so he could see a couple of easy touchdowns.