Houston Texans
DeAndre Hopkins (Wide Receiver): Hopkins has been a bit of an enigma for the last 3 weeks. Hopkins has seen single digit targets for the last 3 weeks and has only hauled in 1 touchdown in that time frame. The Colts give up the 5th most fantasy points against wide receivers so it is very possible Hopkins has a huge game. With T.J. Yates likely to be the starter for this contest Hopkins may be in line for a ton of targets. The last time Yates played with Hopkins he had 12 targets.
Indianapolis Colts
TY Hilton/Donte Moncrief (Wide Receivers): Hilton and Moncrief will face a secondary that gives up the 10th fewest fantasy points to wide receivers this season. Hilton is coming off of a monstrous game where he put up 100+ yards but immediately we may need to pump the breaks. Hilton has had terrible fantasy weeks after a big game since we have hit the last half of the season. In week 7 he dominated but in week 8 he disappeared. In week 9 he was a bit more effective and after the Colts bye in week 11 he was back to nothing. Weeks 12 and 13 were also the same in pattern. So now coming off of a 132 yard game it should be assumed that Hilton quiets down especially in a difficult matchup. Hilton is a sit. Considering we are not 100 percent sure who will be starting at quarterback for the Colts it might be best to sit Moncrief as well.
Frank Gore (Running Back): Gore has been deteriorating all season long and we have finally reached his breaking point. He has not hit 100 yards all season long either so maybe the writing is on the wall. Gore has not seen the end zone since week 9 but may have an easier time of finding it this week as he faces a defense that has given up the 12th most fantasy points to running backs. Gore would be an extremely risky play at such an important stage of the fantasy season.