Tennessee Titans:
Antonio Andrews (Running Back): The Patriots are giving up the 10th fewest fantasy points to opposing running backs and Andrews production is at an all-time low. The Titans would have to keep this game relatively close for him to even have a shot at being relevant.
Delanie Walker (Tight End): Walker is the leader in targets for the Titans and Marcus Mariota's safety net. The Patriots allow the 4th fewest fantasy points to wide receivers but Walker will have a ton of targets. Walker has 25 targets in the last two weeks and will likely get a ton more with the Titans likely having to play catch up.
New England Patriots
Tom Brady (Quarterback): Brady has Gronkowski back and that makes a world of difference. The Titans allow the 5 most fantasy points to quarterbacks and their defense has allowed 28 passing touchdowns. Brady has 8 touchdowns in his last 3 games.
Danny Amendola (Wide Receivers): The Titans have allowed the 8th most fantasy points to wide receivers without Jason McCourty on the field and their defense allowed 263 yards and 3 touchdowns in week 14. Amendola should see double digit targets.
Brandon Bolden/James White (Running Backs): White will be the passing down back while Bolden will be the early down back. Bolden has a chance to fill the LeGarrette Blount role while White will fit the Dion Lewis role. The Patriots seem to be pretty straightforward about this setup so expect White to see a lot of targets while Bolden sees a lot of carries.