Tottenham will look to tighten their grip on thr final Champions League place, while Everton will be keen to get right on the tails of their opponents when the two teams clash at Goodison Park in their English Premier League game.
Spurs are in fourth on 26 points on the back of a good run, but Everton, who have had two tough outings against Arsenal and Manchester City, are just three points behind on 23 points.
"I think Tottenham have always been there or thereabouts," Everton manager David Moyes said. "They've set their club up and their team up to try to be in Europe.
"They were great in the Champions League with Harry (Redknapp) a year or so ago and this year they've done well to qualify for the next stages of the Europa League.
"Tottenham you would always see as one of the clubs who will be competing at the top end of the league. To finish above Tottenham would give you a great chance to be in Europe, that's for sure.
"But I think Tottenham are a good side with some really good players, so it will be a big challenge for us."
Moyes insisted it was still too early to make judgements on what the Premier League table will look like at the end of the season, as the Toffees look to make a charge for a Champions League spot.
"We're still quite early, we're not into Christmas time and a lot will change over the next month or two," he added. "You don't need to be right up there right away, though I'd like to be.
"I knew this was going to be a difficult period but I'm pleased with the way we've played, especially against Arsenal and Manchester City.
"I think in both games there were periods where we could have won the game and also periods where I was happy with how we defended, so I'll go into this game with a lot of confidence and faith that the team will go and produce another good performance."
Kevin Mirallas and Seamus Coleman have an "outside chance" of featuring against Spurs, according to Moyes, while Phil Neville and Victor Anichebe remain ruled out.
For Tottenham, Michael Dawson is expected to miss out, while Gareth Bale is definitely ruled out. Beniot Assou-Ekotto and Scott Parker are still a week away from a return.
To watch Everton vs Tottenham Live Stream, click here.
Expected lineups: Everton: Howard; Hibbert, Jagielka, Distin, Baines; Osman, Gibson, Naismith, Pienaar, Fellaini; Jelavic.
Tottenham: Lloris; Naughton, Gallas, Caulker, Vertonghen; Sandro, Dembele, Lennon, Dempsey; Adebayor, Defoe.
Prediction: 2-1 to Everton
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