Tottenham will look to go two points clear of Chelsea and into third place when they travel to West Ham in their English Premier League game Monday.
Spurs, who are unbeaten in ten Premier League games, are primed to take advantage of Chelsea's slipup against Manchester City Sunday and all eyes will again be on Gareth Bale as he continues to wow with his prowess.
The three points will also be important for Andre Villas-Boas' side, with Arsenal just a point behind their North London rivals after their 2-1 win over Aston Villa Saturday.
January signing Lewis Holtby said he was looking ahead to playing in his first London Derby, as Spurs warm-up for the big North London Derby against Arsenal next Sunday.
"It's an important game for everyone, for the fans, for West Ham, for us, sitting in fourth spot and trying (to) reach third, it's a vital game," Holtby told the club's official website.
"I can't wait and we've two massive games in a row now, West Ham and Arsenal. It doesn't get better than that! I'm already buzzing for those games."
West Ham are not on the greatest of runs at the moment, but with injury worries easing up for Sam Allardyce, the Hammers might be ready to go on a winning streak of their own, although they will have to keep a close eye on Bale.
"Gareth Bale has been the major difference between Tottenham and the teams they've played recently. Not only has he scored very important goals, but they've been stunning goals at that.
"He's going to need some looking after on Monday night. If we can do that we nullify a threat that Tottenham have. Of course (Aaron) Lennon is a threat down the other side, but he doesn't quite score as many goals as Gareth Bale.
"We're not sure yet whether Jermain Defoe will be fit, but certainly we've got to cope with that strike force. Our home form has been excellent all season and so we're going to hopefully make sure Tottenham worry about us for a long period of time on Monday night, rather than us worry about them too much."
Spurs striker Jermain Defoe will not be available, along with Sandro, Tom Huddlestone and Younnes Kaboul.
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Expected lineups: West Ham: Jaaskelainen; O'Brien, Reid, Collins, Pogatetz; Noble, Diame; Taylor, Nolan, Cole; Carroll.
Tottenham: Lloris; Walker, Dawson, Vertonghen, Naughton; Dembele, Parker; Lennon, Holtby, Bale; Adebayor.
Prediction: 2-2