Manchester United will want to make up for last season's 6-1 loss when they take on Manchester City in the English Premier League Monday.
United have as good as won the Premier League title, and currently hold a 15-point lead at the top over City. However, they have had disappointments off late, after seeing their double dream end with a 1-0 loss to Chelsea in the F.A. Cup quarterfinals last Monday.
Ferguson, though, insisted winning the league title would still be a fantastic achievement, after some people suggested United's season had as good as ended following that defeat to Chelsea, with the title race for the Premier League pretty much done.
"I was asked about only winning one trophy," he told the club's official website. "I think that's a strange question in the context of the kind of competition we have as we're up against teams from London -- Arsenal, Tottenham and Chelsea -- plus Liverpool and Everton.
"They're massive challenges every year (for both Manchester clubs). For every one of those teams, the supporters want to win one trophy. I think we can win the one that really does matter to the fans in particular.
"Yes, I'd love to win the Champions League again but I'd say that we were knocked out in circumstances everyone is still talking about. The disappointment at being knocked out by Chelsea is obvious but the league form has been fantastically consistent."
United will be without defenders Jonny Evans and Nemanja Vidic, but Wayne Rooney returns after a two-game absence through injury.
"Vida got injured at Sunderland," Ferguson said. "Early on, he had a clash and had a bit of treatment and then he had a clash with David De Gea near the end of the game. It's not serious, just a nerve in his calf, so he should be maybe back in training over the weekend.
"I've got Rio Ferdinand, Chris Smalling and Phil Jones so I've got the right cover, I think."
City will have to do without Micah Richards, Jack Rodwell and Maicon, but Samir Nasri and David Silva have been passed fit after picking up minor knocks in the previous game against Newcastle.
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Expected lineups: Manchester United: De Gea; Rafael, Ferdinand, Jones, Evra; Carrick, Giggs; Young, Rooney, Welbeck; Van Persie.
Manchester City: Hart; Zabaleta, Kompany, Nastasic, Clichy; Barry, Toure; Milner, Silva, Nasri; Tevez.
Prediction: 2-2