All eyes will be on David Moyes as he begins a new era at Manchester United when the reigning English Premier League champions travel to Wales to take on a dangerous Swansea side.
The late kick-off of the action on Saturday will be enthralling to say the least not just because of all the pressure of Moyes to deliver and continue the legacy left by Sir Alex Ferguson, but also because of the Wayne Rooney factor.
It is expected Moyes might name Rooney on the bench after the 27-year-old played over an hour for England in the friendly win over Scotland on Wednesday.
United could not have been handed a tougher early fixture list with the champions set to face Liverpool, Manchester City and Chelsea within the first five games of the season.
However, Moyes will be concentrating on getting a positive result against Swansea first, with the Welsh side easily capable of creating an upset on opening day.
"It's a very tough away fixture," Moyes told MUTV. "Michael Laudrup has done a really good job there and strengthened the team a lot this summer.
"I would expect Swansea to have another season as good as last year and they've already had a couple of European games as well which gives them the feeling they are a little more match-ready.
"We know it will be a hard game but we feel we're getting ready as well and getting everybody back fit. Because of that, hopefully we'll go there and give ourselves a good chance of winning.
"The only real injury we've had is Rafael's that looks like keeping him out for four-to-six weeks with a hamstring. We've had a few other small niggles, keeping people out for a few days, but, hopefully, most people will be available and ready for the game."
Swansea will be without Dutch international midfielder Jonathan De Guzman, but Michael Laudrup will still have plenty of firepower at his disposal to cause a few problems.
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Expected lineups: Swansea: Vorm; Rangel, Williams, Chico, Davies; Britton, Canas; Routledge, Michu, Dyer; Bony.
Manchester United: De Gea; Jones, Ferdinand, Vidic, Evra; Giggs, Carrick, Cleverley; Zaha, Van Persie, Welbeck.
Prediction: 2-1 to United
