New England Patriots
Rob Gronkowski (Tight End): Gronkowski had a quiet week 5 as Dallas held him under 10 fantasy points. Gronk will return to form against the Colts toothless defense especially after Deflategate. Gronk is a TE1 for his matchup with the Colts.
Tom Brady (Quarterback): Brady is playing at a record setting pace and should continue to see that level of production against the Colts defense. This matchup is perfect for Brady owners so expect him to go off against the team that labeled him a cheater.
Julian Edelman (Wide Receiver): Edelman has been pretty solid this season; he has been the only wide receiver for the Patriots to actually have an impact on offense. Edelman should continue to dominate in an easy matchup with the Colts.
Dion Lewis/LeGarrette Blount (Running Back): Lewis is clearly the favorite back when Brady is passing the ball. He has double digit fantasy production every week and should find some holes against this Colts defense. Blount on the other hand is a power back that lulls defenses to sleep; Blount is a constant threat to score around the goal line. I love their matchup but the Patriots passing offense should carry the load in this game.
Indianapolis Colts
TY Hilton/Donte Moncrief/Andre Johnson (Wide Receivers): The key person to start here is TY Hilton and even then I don't see him going off with Andrew Luck just quite yet. Hilton should have a solid double digit game but should stay out of the end zone. The battle between Moncrief and Johnson for the 2nd starting wide receiver spot is about to heat up, unless all Johnson wanted to do was punish his former team. If Johnson just wanted to go off against the Texans than his value is set for the rest of the year but for owners of either I would be wary. Moncrief owners received a huge dud in week 5 that had them searching for answers. This Colts passing game should provide them in week 6.
Frank Gore (Running Back): Gore is coming off of his best game of the season however he is facing a Patriots defense that has given up the 9th fewest fantasy points to running backs. This should not come as a surprise as the Patriots have looked stout on defense. Gore has a tough matchup and the Patriots will likely be ahead for most of this game. The Colts will have to throw the ball in order to keep up, Gore should return to earth this week.
Andrew Luck (Quarterback): Luck has not played well, at all. I don't know if he was injured prior to the season but when Blake Bortles or Marcus Mariota (a rookie no less) is playing better than you something is extremely wrong. Luck owners this might be the day you have been waiting for as he seems healthy enough to lead this Colts offense to some points. I am not sold on Luck this week but he should have a productive game. If he doesn't bounce back the Colts will be in big trouble.