Atlanta Falcons
Julio Jones (Wide Receiver): San Francisco has given up the 8th most fantasy points in the NFL and Jones is coming off of an incredible game against the Buccaneers where he had almost 200 yards. Jones has seen double digit targets in the last 4 games so it is likely he will be Ryan's prime option in this favorable matchup.
Devonta Freeman (Running Back): Freeman has a great matchup against the hapless 49ers. This defense is a bad joke and in the last 4 weeks Devonta Freeman has only had one game where he didn't rack up 100 yards. Last week's aberration was due to the fact that the Falcons were behind so things should go a bit more smoothly against Blaine Gabbert and the 49ers.
Matt Ryan (Quarterback): The only thing to worry about in this matchup is how long this game will be competitive. The Falcons need a get well game in the worst way after losing to the lowly Bucs partly because of Ryan's propensity to turn the ball over. Ryan will need to keep it clean and the 49ers will need to keep things competitive for Ryan to be productive.
San Francisco 49ers
Pierre Thomas/Shaun Draughn (Running Back): Thomas and Draughn were literally thrown in as starters for this game. The 49ers might be tanking their season for a high draft pick because there is no logical reason to start Blaine Gabbert over Kaepernick. With that said the 49ers should run the ball a ton so Pierre Thomas is worth a roster spot.
Torrey Smith/Anquan Boldin (Wide Receivers): Blaine Gabbert is starting at quarterback and the Falcons have given up the 3rd fewest points to fantasy wide receivers, you can do better.