Indianapolis Colts
TY Hilton/Donte Moncrief (Wide Receivers): The Steelers have given up the 3rd most fantasy points to wide receivers this season. Hasselbeck has great chemistry with both wide receivers however Hilton has been on fire since Hasselbeck has come under center. Hilton had 2 touchdowns last week and saw double digit targets while Moncrief had his first 100 yard game since week 2. These receivers should continue to trend upward as long as Hasselbeck is the quarterback.
Frank Gore (Running Back): The Steelers have allowed the fewest fantasy points to running backs and Gore really isn't in the condition to challenge this strong run defense. Indianapolis head coach Chuck Pagano even said that Gore was "beaten up"....... not a great sign for fantasy owners.
Pittsburgh Steelers
Antonio Brown/Martavis Bryant (Wide Receivers): The Colts have allowed the 15th most fantasy points to wide receivers. Owners do not have to worry about a backup quarterback effecting Brown or Bryant's play as it is assumed Roethlisberger will start since he has begun practicing today. The Colts are 27th against the pass and allow 272.8 passing yards per game so both of these guys are excellent options. Bryant has had 100 total yards or a touchdown in 5 out of the 6 games he has played in since returning from his suspension.
Ben Roethlisberger (Quarterback): The Colts have given up the 15th most fantasy points to quarterbacks which means Big Ben should be a top 5 option this week. The Colts do allow 272.8 passing yards per game so Roethlisberger should have a pretty easy time throwing against them.
DeAngelo Williams (Running Back): The Colts have given up the 13th most fantasy points to running backs this season which gives Williams an excellent matchup to find some decent production. Williams has had either 1000 total yards or a touchdown in 5 out of 6 games he has started in this season making him one of the more productive running backs in the past few weeks. Williams is a solid RB2 with RB1 upside.