San Francisco 49ers
Shaun Draughn (Running Back): The Browns have allowed the 6th most fantasy points to running backs making this an insanely attractive option. Draughn has been solid filling in for Carlos Hyde while he is out with an injury. After 3 solid outings he should torch one of the top 5 run defenses in the league.
Torrey Smith/Anquan Boldin (Wide Receivers): Smith is absolutely irrelevant unless this game goes into overtime. His numbers last week were inflated by a walk off overtime touchdown. The Favorite target in this offense is Anquan Boldin as he has been targeted a team high all season long. The Browns give up the 6th most fantasy points to wide receivers so expect Boldin's numbers to see an uptick.
Cleveland Browns
Duke Johnson Jr (Running Back): The 49ers have given up the 3rd most fantasy points to running backs all season long and not only can he run but he can catch passes. Manziel should have to check down quite a few times in this game which could lead to some solid production as demonstrated by Buck Allen. Johnson is a low end RB3.
Gary Barnidge (Tight End): Barnidge has been incredibly shaky from a fantasy perspective as soon as Manziel hits the field. With him starting for the rest of the way, Barnidge could see his fantasy value decline significantly. Barnidge also rolled his ankle in last week's game making him questionable for this week 14 matchup.
Travis Benjamin (Wide Receiver): Benjamin suffered a shoulder injury in week 13 and could not finish the game. Benjamin has missed practice on Wednesday so he should come down to the wire in regards to his playing status.