With progress into the knockout rounds of the Champions League secured, a youthful Manchester United side will look to play spoilsport against Galatasaray in the cauldron that is Istanbul.
Sir Alex Ferguson has chosen to rest most of his senior players, with the likes of Robin Van Persie, Wayne Rooney, Rio Ferdinand, Ryan Giggs and Paul Scholes all remaining in Manchester, as the young brigade of United look to impress.
Galatasaray, on the other hand, have everything to play for, with the Turkish club equal on point with CFR Cluj and one point ahead of Braga.
Second place in Group H is very much up for grabs, meaning Galatasaray will go all out for a win against an under-strength United side.
"Our group is very complicated," Galatasaray manager Fatih Terim said. "There are two teams on four points and one team with three. Unfortunately we gave away those three points (when losing at home to Braga).
"At the start of the campaign, I said that every goal scored and every goal conceded would count. Now we see this becoming a reality. If we had drawn against Braga, we could have guaranteed our place in the next round by beating United.
"The best thing now is us and Cluj winning tomorrow. That will give us a great advantage if no guarantees. At least, we'd have an advantage before the final match (in Braga).
United are no strangers to the Turkish atmosphere, having felt the brunt of it a couple of times before, especially in 1993, and Ferguson will see who among his young squad step up to the plate. "Our players have played challenging games in various parts of the world and I believe they will be at their best," Ferguson said. "We don't consider the young players a gamble.
"What we do consider is our reputation and we have to be fair to the other teams in the group. We are very conscious of how to pick our team. It will be a good occasion to see our young players introduce themselves to the public and the media. Our aim is to win.
"In the UEFA Champions League this season, we saw some interesting results, like Celtic beating Barcelona and BATE defeating Bayern Munich. Those occasions show the increasing quality of the Champions League.
"In 1993 (when United first visited Galatasaray), the atmosphere was incredible. We've been here a few times and we've seen Turkish enthusiasm and passion. It's fantastic."
United will welcome back Phil Jones from injury, with the defender set to make his first appearance this season. However, playmaker Shinji Kagawa has not quite progressed from his knee injury, and will be out for another month.
Galatasaray has no major injury problems going into the game, with Terim considering making a couple of changes to the team that played Karabukspor at the weekend.
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Expected lineups: Galatasaray: Muslera; Eboue, Nounkeu, Cris, Hakan Balta; Hamit Altıntop, Selcuk Inan, Melo, Emre Colak; Yılmaz, Elmander 46.
Manchester United: Lindegaard; Rafael, Jones, Smalling, Buttner; Fletcher, Anderson, Cleverley; Young, Welbeck, Hernandez.
Prediction: 2-1 to Galatasaray
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