New York Giants
Odell Beckham JR (Wide Receiver): ODB is out for the championship week which is a gigantic blow to any fantasy team with him on the roster. Odell's suspension could not only kill your fantasy championship but as well as the Giants bid for an NFC East championship.
Eli Manning (Quarterback): Manning's value goes dramatically down this week with Beckham being suspended. It would be shocking to see Manning get 4 touchdowns this week against one of the better defenses in the league. This defense gives up the 15th fewest points to opposing quarterbacks giving Manning a pretty tough matchup this week. Manning should be sat in week 16.
Minnesota Vikings
Adrian Peterson (Running Back): The Giants give up the 9th most fantasy points to running backs and with Peterson limited all week it will be tough to put him in as an RB1 this week. The Giants allow 114.6 yards to opposing running backs but Peterson has been held to under 70 rushing yards in the past 3 weeks. Peterson will be hard to trust but he may end up surprising owners with a big game.
Stefon Diggs (Wide Receiver): The Giants give up the 4th most fantasy points to opposing wide receivers and Diggs had 2 touchdowns last week. The Giants allow 308 passing yards per game and are easily the league's worst secondary. Diggs has 3 or fewer catches in the last 3 games however he has what could be his best matchup of the season. With Adrian Peterson banged up Teddy Bridgewater could rely on his big play wide receiver for the majority of the Vikings offense.