Arsenal and West Ham United will both look to correct their recent mishaps when they clash at the Emirates Stadium .
Manager Arsene Wenger has a problem in midfield as Mikel Arteta (calf), Francis Coquelin (hamstring), and Tomas Rosicky (calf) are all out.
Defensive midfielder Abou Diaby (thigh) will have a test, but forward Gervinho is away at the African Nations Cup and goalkeeper Lukasz Fabianski out with a foot injury.
The Gunners will be boosted by a spirited second-half display during their recent 2-1 defeat to Chelsea in the Premier League. West Ham boss Sam Allardyce, meanwhile, will be hoping he can maintain his good record against his arch-nemesis Wenger.
It is not known whether any of the Hammers' recent new signings will feature - Wellington Paulista is not expected to be ready to start, even though West Ham are light on strikers with Andy Carroll out and Marouane Chamakh ineligible, although the Brazilian could have a place on the bench.
The Gunners are unbeaten in their last 10 games with the Hammers, winning eight. One of Wenger's side's most impressive results of the season came with a 3-1 victory at Upton Park back in October.