With their lead at the top of the table trimmed to just two points, defending Serie A champions Juventus will be desperate to pick up all three points against local rivals Torino.
The Turin Derby will be crucial for both sides, as Juve look to establish a firm lead at the top, while their opponents look to stay out of relegation trouble.
"We have been waiting for this game for a long time," Juve midfielder Claudio Marchisio told Sky Italia. "Not only us, but also the Torino players, our fans, the city, so it is great to have such an important match again.
"We are playing (the derby) in our own stadium for the first time so we know we will have the fans behind us, and we will try to give it our best.
"This is the only game on our minds because it is the most important one for now.
"Every game is decisive so right now we are only thinking of the league, and then we will think of Shakhtar (in the Champions League).
Torino manager Giampiero Ventura said his team was honored to play Juventus.
"We are honoured to go to the Juventus Stadium and we go there humble enough to know we are facing the strongest team, but at the same time we are aware that if we do our best, well then it will be the result to decide things," he told reporters.
"It's going to be tough for us. There is an obvious difference in the value of these two clubs, but we are still delighted to play this game.
"We are up against the strongest side around and it is a derby, for which they are going to be determined as always."
Juventus will welcome back Giorgio Chiellini after the defender missed the 1-0 loss to Milan last weekend, while Martin Caceres is ruled out. Arturo Vidal is also doubtful.
To watch Juventus vs Torino Live Stream, click here.
Expected lineups: Juventus: Buffon, Barzagli, Bonucci, Chiellini, Lichtensteiner, Pogba, Pirlo, Marchisio, Asamoah, Vucinic, Giovinco.
Torino: Gillet; Darmian, Glik, Ogbonna, D'Ambrosio, Basha, Gazzi, Cerci, Bianchi, Meggiorini, Santana.
Prediction: 3-1 to Juventus
(**Sports World Report does not endorse the live streaming of the games of the sites it has linked to. It has no control over the content of the website and thus does not warrant that it is error or virus free or free of other harmful components.)